By H.-J. Biersack (auth.), Hans Bender MD, Holger Palmedo MD, Hans-Jürgen Biersack MD, Peter E. Valk MD (eds.)
Clinical reports in the past 10 years have proven that puppy is extra delicate than CT and MRI for the detection of many tumors. in lots of situations, notwithstanding, for instance in head and neck tumors, mix with radiological techniques is critical. it can be speculated that puppy may be the 1st research in a malignant tumor whilst metastatic unfold is suspected. MRI and CT may perhaps then be limited to these physique parts which evince websites of elevated glucose metabolism. hence, a mixture of metabolic and morphologic approaches will increase tumor detection and alter the healing approach. during this gentle, an atlas together with puppy, CT, MRI, and histology info turns out fascinating to mix metabolic and morphologic imaging. This publication offers an outline of the on hand information which might be of serious curiosity not just for experts in radiology and nuclear medication, but additionally for oncologists.
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Extra info for Atlas of Clinical PET in Oncology: PET versus CT and MRI
4 Distant Metastases Figure 16a-c Diagnosis: Oropharynx carcinoma with lymph node and bone metastases. Patient and History: 51-year-old patient with palpable cervical lymph nodes due to a confirmed oropharynx carcinoma. Technique: Transmission-corrected scans with a slice thickness of 4 mm, image reconstruction by filtered backprojection. PET Results: Series (a-c) of coronal (I), transaxial (II) and sagittal (III) PET views show a focus in projection on the primary (oropharynx) (I-ilia), multiple left cervical foci (LN) (I-III b) and a solitary focus in the left humerus (I-III c).
JNucl Med 38:1196-1201 13. Valk PE, Abella-Columna E, Haseman MK, et al. (1999) Whole-body PET imaging with F-18-fluorodeoxyglucose in management of recurrent colorectal cancer. Arch Surg 134:503-511 14. Beets G, Penninckx F, Schiepers C, et al. (1994) Clinical value of whole-body positron emission tomography with [18Fjfluorodeoxyglucose in recurrent colorectal cancer. Br J Surg 81 15. Vitola JV, Delbeke D, Sandler MP, et al. (1996) Positron emission tomography to stage metastatic colorectal carcinoma to the liver.
Sensitivity for detection of hepatic recurrence was 95 % and 83 % for PET and CT respectively, and for pelvic recurrence, 97% and 63 % respectively. Valk et al. also compared sensitivity and specificity of PET and CT by site of recurrence, and determined the 95% confidence interval for the difference between the two modalities for each site (Table 1) . PET was significantly more sensitive than CT overall. The largest difference between the two modalities was found in the abdomen and pelvis, where over one-third of sites that Table 1.
Atlas of Clinical PET in Oncology: PET versus CT and MRI by H.-J. Biersack (auth.), Hans Bender MD, Holger Palmedo MD, Hans-Jürgen Biersack MD, Peter E. Valk MD (eds.)