W. G. van Aken (auth.), C. Th. Smit Sibinga, P. C. Das, J.'s Alternative Approaches to Human Blood Resources in Clinical PDF

By W. G. van Aken (auth.), C. Th. Smit Sibinga, P. C. Das, J. C. Fratantoni (eds.)

ISBN-10: 1461375711

ISBN-13: 9781461375715

ISBN-10: 1461556198

ISBN-13: 9781461556190

Currently blood is a risky factor. the security of blood and the quantification of transfusion hazards were dominant issues that experience motivated the advance of other ways during this swiftly constructing sector. In medical medication traditional blood and its parts are utilized in supportive cures depending on the alternative of obvious uncritical set off components. A compounding issue is intensity of potential medical trials for facts. Such trials in severe care components will be of large worth, not just in recording adversarial results and under-transfusion, but additionally indicating the worth of choice research and cost-effectiveness in transfusion perform. replacement methods contain using cytokines, progress components, humanised monoclonal antibodies, recombinant plasma components, and buffy coat derived traditional human interferons. those are being more and more carried out within the sanatorium. recommendations for oxygen shipping are being built and fibrinogen lined microcapsules are being investigated for thrombocytopenia. In surgical sufferers, a variety of crystalloid and colloid combos are explored as quantity replacements. to prevent allogeneic transfusions, worthwhile blood saving equipment comprise quite a few techniques, similar to autologous deposits, normovolemic haemodilution and numerous brokers together with aprotinin, tranecamic acid, desmopressin and erythropoietin, yet their use in sanatorium indicates massive adaptations. That umbilical twine blood can be a major resource of allogeneic stem cells in similar and unrelated transplantation is illustrated via the expanding variety of twine blood banks in Europe and somewhere else. destiny blood assets are inclined to face a number of demanding situations: quick demanding situations relate to elevated regulatory and political oversights; intermediate ideas would provide a few advancements in public healthiness and alleviate public worry yet not really tackle the industrial demanding situations thrust upon the remedy method.
As we method the 12 months 2000, the foremost issues approximately transfusion medication stay its logistics, safeguard and effectiveness. This subject is gifted within the complaints of the twenty second foreign Symposium on Blood Transfusion, constructed in 21 up to date issues, accumulated and mentioned in 4 sections.
This ebook might be of well timed worth to scholars, pros and all others or occupied with the sector of transfusion drugs, no matter if scientific or related.

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Additional resources for Alternative Approaches to Human Blood Resources in Clinical Practice: Proceedings of the Twenty-Second International Symposium on Blood Transfusion, Groningen 1997, organized by the Red Cross Blood Bank Noord Nederland

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Transf Med Rev 1994;8:169-83. 115. Linden JV, Paul B, Dressler KP. A report of 104 transfusion errors in New York State. Transfusion 1992;32:601-6. 116. LeLorier J, Gregoire G, Benhaddad A, Lapierre J, Derderian F. Discrepancies between meta-analyses and subsequent large randomized, controlled trials. N Engl J Med 1997;337:536-42. 117. Lemmer JH Jr. Reporting the results of blood conservation studies: The need for uniform and comprehensive methods. Ann Thorac Surg 1994;58: 1305-6. * The International Study of Peri-operative Transfusion ([SPOT) Investigators are the following: Coordinating Centre and Canadian Investigators Phil Wells, MD; George Wells, PhD; Fraser Rubens, MD; Annette O'Connor, PhD; Laura McAuley BSc; Andreas Laupacis, MD (Chair); Jack Kitts, MD; Paul Hebert, MD; Ian Graham, PhD; Dean Fergusson, MHA (Coordinator); Greg Bryson, MD.

O. Benavente, J. Cooper, J. Pagliarello, O. Rosaeg, and B. Schmidt, and Ms. B. Malanka for translating some of the articles, Dr. Malcolm Ring for help with abstracting data from studies, Ms. Jesse McGowan, Ms. Shin and Ms. June MacLeod for assistance with the literature searches, and Mrs. Karen Weeks for her secretarial assistance. References I. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. Laupacis A, Fergusson D, for the International Study of Peri-operative Transfusion (ISPOT) Investigators. Drugs to minimize peri-operative blood loss in cacrdiac surgery - Meta-analyses using peri-operative blood transfusion as the outcome.

Eur J Cardio-thorac Surg 1995 ;9:206-1 O. 40. Dietrich W, Dilthey G, Spannagl M, Jochum M, Braun SL, Richter JA. Influence of high-dose aprotinin on anticoagulation, heparin requirement, and celite- and kaolinactivated clotting time in heparin-pretreated patients undergoing open-heart surgery. Anesthesiology 1995;83:679-89. 41. D'Ambra MN, Akins CW, Blackstone E, et al. Aprotinin in primary valve replacement and reconstruction: A multicenter, double- blind, placebo-controlled trial. J Thorac Cardiovasc Surg 1996;112: 1081-89.

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Alternative Approaches to Human Blood Resources in Clinical Practice: Proceedings of the Twenty-Second International Symposium on Blood Transfusion, Groningen 1997, organized by the Red Cross Blood Bank Noord Nederland by W. G. van Aken (auth.), C. Th. Smit Sibinga, P. C. Das, J. C. Fratantoni (eds.)


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