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By Ann S. Masten, Norman Garmezy (auth.), Benjamin B. Lahey, Alan E. Kazdin (eds.)

ISBN-10: 1461398207

ISBN-13: 9781461398202

ISBN-10: 1461398223

ISBN-13: 9781461398226

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MASTEN AND NORMAN GARMEZY Schulsinger, & Mednick, 1971), but the specificity of this finding to schizophrenia as opposed to the severity of the mother's illness irrespective of her type of disorder has been debated (Sameroff, Seifer, & Zax, 1982). • Earlier reports of deviant psychophysiological functioning in children at risk have lacked robustness, but there have been recent reports of a diminished P300 amplitude, a late component of the human average evoked potential in adult schizophrenic patients (Morstyn, Duffy, & McCurley, 1983) and in children at risk for schizophrenia (Friedman, Vaughn, & Erlenmeyer-Kimling, 1982).

In the schizophrenia literature, for example, there are studies of children at risk for this disorder, identified by the risk factor of a biological parent who has the disorder. There is also an intense research effort directed at finding markers that would identify children vulnerable to schizophrenia. The focus is broader in studies of risk factors associated with various maladaptive outcomes. The risk factor itself may be quite narrowly defined or broad but the focus is not on a single outcome.

Findings such as these require caution. When one considers the huge array of variables that may be and have been introduced into risk research studies, the indications that differentia tors appear to exist may prove to be due to artifacts or to chance occurrences unless there are replications across laboratories. But selection of variables too cannot be left to chance and in future studies of children at risk a more theoretical basis for selecting measures will be needed. A step in this direction has been taken by Zubin and Spring (1971) in their proposal to search for markers of vulnerability-which they view as a more fundamental trait component in those individuals truly at risk for the development of schizophrenia.

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Advances in Clinical Child Psychology by Ann S. Masten, Norman Garmezy (auth.), Benjamin B. Lahey, Alan E. Kazdin (eds.)

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